When should a built-in Optimize targeting condition (all targeting conditions except for Google Analytics Audiences) be used over an Analytics audience when the data is available via both targeting methods? e.g. Browser

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When should a built-in Optimize targeting condition (all targeting conditions except for Google Analytics Audiences) be used over an Analytics audience when the data is available via both targeting methods? e.g. Browser

1.  A)  When the condition is based on current, real-time behavior, a built-in Optimize targeting condition is the best practice.
2.  B)  When the condition requires multiple AND statements, a built-in Optimize targeting condition is the best practice.
3.  C)  When the condition requires multiple OR statements, a built-in Optimize targeting condition is the best practice.
4.  D)  When the condition is based on historical data, a built-in Optimize targeting condition is the best practice.